Abbreviation: COL2A1
Target Synonym: COL2A1;ANFH;AOM;COL11A3;SEDC;STL1
Conjugation: Unconjugated
UNIProt ID: P02458
Background: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human COL2A1
Dilution: WB 1:500-1:2000,IF 1:50-1:200
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