Cortactin Polyclonal Antibody, Rabbit

Abbreviation: Cortactin

Target Synonym: CTTN;EMS1;cortactin

Conjugation: Unconjugated

UNIProt ID: Q14247

Background: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human Cortactin

Dilution: WB 1:500-1:2000,IF 1:50-1:200

• SKU: ELSE-AB-92678-200
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92678-200
• Green Labware: No
• Package Unit: 200 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Immunofluorescence, Western Blotting
• Isotype: IgG
• Host: Rabbit