Formulation: A solid
Formal Name: N-[1,2,3,4-tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4′-(trifluoromethyl)- [1,1′-biphenyl]-2-carboxamide
Purity: ≥98%
Formula Markup: C26H22F3N5O
Formula Weight: 477,5
Shelf life (days): 1460
CAS Number: 186390-48-7
Notes: CP 346,086 is an inhibitor of microsomal triglyceride transfer protein (MTTP; IC50 = 2 nM).{69476} It inhibits apolipoprotein B (ApoB) and triglyceride secretion in HepG2 cells (IC50 = 2.6 nM for both). CP 346,086 (10 mg/kg) lowers plasma triglyceride levels, as well as plasma total, VLDL, and LDL cholesterol levels in rats.