Formulation: A solid
Formal Name: N-(aminoiminomethyl)-N-methyl-glycine, monohydrate
Purity: ≥95%
Formula Markup: C4H9N3O2 • H2O
Formula Weight: 149,1
Shelf life (days): 1460
CAS Number: 6020-87-7
Notes: Creatine is a derivative of the amino acid glycine.{72033} It is produced from glycine and L-arginine by arginine:glycine amidinotransferase (AGAT) and guanidinoacetate N-methyltransferase (GAMT) via a guanidinoacetate intermediate. Creatine circulates in the blood and enters tissues via the creatine transporter. In tissues, it is phosphorylated to creatine phosphate (Item Nos. 35598 / 37803), which is used as a reservoir of phosphoryl groups that can be transferred to ATP for the first few seconds of energy consumption, particularly in high-energy consumption tissues such as the brain and skeletal muscle.{72034} Decreased brain levels of creatine are associated with inborn errors of creatine metabolism characterized by deficiency of AGAT, GAMT, or the creatine transporter.{72033}
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