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Clone Name: MSVA-605M
Light Chain: Kappa
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 62
Positive Control: Tonsil: A moderate to strong cytoplasmic KRT5 staining should be seen in virtually all squamous epithelial cells. Prostate: A strong cytoplasmic staining should be present in the majority of basal cells.
Negative Control: Tonsil: Lymphatic cells must not show any KRT5 positivity.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Uniprot ID: P13647
Antigen Species: Human
Immunogen: Recombinant fragment (around aa 316-590) of human Cytokeratin 5 (KRT5) protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: keratin 5
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