Clone Name: 43DAG1/8D5
Application Note: IHC-Fr: 1:50–1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 97
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Nov 2015]
Uniprot ID: Q14118
Antigen Species: Human
Immunogen: Synthetic peptide containing 15 of the last 16 amino acids at the extreme C-terminus of the human beta-dystroglycan sequence (PKNMTPYRSPPPYVP-PCOOH).
Purification: Unpurified
Conjugation: Unconjugated
Full Name: dystroglycan 1
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