DBCO-PEG4-Ahx-DM1, CAS 2479378-44-2

Product Description: DBCO-PEG4-Ahx-DM1 is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DBCO-PEG4-Ahx-DM1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C68H89ClN6O17

CAS Number: 2479378-44-2

Molecular Weight: 1297.92

Compound Purity: 94.44

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-136260-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136260-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK