DC1SMe, CAS 501666-85-9

Product Description: DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

Applications: Cancer-programmed cell death

Formula: C35H30ClN5O4S2

References: [1]Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.

CAS Number: 501666-85-9

Molecular Weight: 684.23

Compound Purity: 98.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin

• SKU: MEXHY-112898-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112898-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK