Product Description: Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
Applications: Cancer-programmed cell death
Formula: C52H56FN9O13
References: [1]NOGUCHI, Shigeru, et al. METHOD FOR SELECTIVELY MANUFACTURING ANTIBODY-DRUG CONJUGATE. WO2017002776A1./[2]Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
CAS Number: 1599440-13-7
Molecular Weight: 1034.05
Compound Purity: 99.94
Research Area: Cancer
Solubility: DMSO : 73.33 mg/mL (ultrasonic)
Target: Drug-Linker Conjugates for ADC