DGN549-C, CAS 2058075-34-4

Product Description: DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-agent conjugates (ADCs)[1].

Applications: Cancer-programmed cell death

Formula: C60H61N9O12

References: [1]Chen Bai, et al. Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates With an Improved Therapeutic Index as Compared With Lysine Conjugation. Bioconjug Chem

CAS Number: 2058075-34-4

Molecular Weight: 1100.18

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-136297-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136297-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK