Formulation: A solid
Formal Name: 1-(6-methoxy-2-naphthalenyl)-3-(3-pyridinyl)-2-propen-1-one
Purity: ≥98%
Formula Markup: C19H15NO2
Formula Weight: 289,3
Shelf life (days): 1460
CAS Number: 104890-70-2
Notes: DMU2139 is an inhibitor of the cytochrome P450 (CYP) isoform CYP1B1 (IC50 = 0.009 µM).{72079} It is selective for CYP1B1 over CYP1A1, CYP1A2, CYP3A4, and CYP2D6 (IC50s = 0.795, 1.2, 10.6, and 5 µM, respectively). DMU2139 enhances cisplatin-induced cell death in HEK293 cells overexpressing CYP1B1.