Clone Name: DJR2-4
Application Note: FACS: 1/10-1/20. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 48
Form: Liquid
Buffer (with preservative): PBS, 0.09% Sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Uniprot ID: O14763
Antigen Species: Human
Immunogen: Extracellular domain of DR5-human IgG1 Fc fusion protein.
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: TNF receptor superfamily member 10b
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