Target: EAAT3
Conjugate: Unconjugated
Product Type: Monoclonal
Clone Number: N180/41 (Formerly sold as S180-41)
Immunogen: Fusion protein amino acids 1-524 (full length) of human EAAC1
Swiss-Prot: P43005
Purification: Protein G Purified
Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Concentration: 1 mg/ml
Specificity: Detects ~60kDa.
Cellular Localization: Membrane
Scientific Background: SLC1A1/EAAT3/EAAC1, a member of this transporter family, is expressed throughout the body, particularly in brain, intestine, liver, heart and kidney. Functional defects of the SLC1A1 gene are found in patients of dicarboxylicamino aciduria.
References: 1. Smith C. P., et al., (1994) Genomics 20:335-336.2. Kanai Y., and Hediger M. A. (1992) Nature 360:467-471.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.