Elab Fluor 488 Anti-Mouse CD122/IL-2RB Antibody(5H4), Rat, Monoclonal

Swissprot: P16297.

Background: CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Abbre: Mouse CD122.

Buffer: PBS with 0.05% Proclin300, 1% BSA.

Clone No: 5H4.

Conjugation: Elab Fluor® 488.

• SKU: ELSE-AB-F1029L-200
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-F1029L-100X2
• Package Unit: 100x2 Tests
• Quantity Unit: PAK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Human Gene ID: 16185
• Host: Rat