Background: Elastin is the major protein of elastic fibres that form a randomly orientated network in many tissues. Due to its high content of hydrophobic amino acids it is relatively resistant to chemicals and proteinase. Its principal function is to provide elasticity to tissues, however it has also chemotactic and cell adhesion properties. Human Elastin 100%, human Collagen Type I, II, III, IV, V <0,1%; human Fibronectin <0,1%.
Positive Control: Human skin or aorta.
Immunogen: Purified elastin from human skin.
Purification Method: Affinity purified antibody lyophilized from phosphate buffered solution; no BSA and preservative added!.
Concentration: app. 1 mg/ml.
References: 1. Demarchez M., Hartmann D.J., Herbage D., Ville G., and Prunieras M. (1987) Wound-healing of human skin transplanted onto the nude mouse. 2. an immunohistochemical and ultrastructural study of the epidermal basment-membrane zone reconstruction and connenc 2. Demarchez M., Hartmann D.J., and Prunieras M. (1987) An immunohistochemical study of the revascularization process in human skin transplanted onto the nude mouse. Transplantation 43; 896-903. 3. Lethias C., Hartmann D.J., Masmejean M., Ravazzola M., Sabbagh I., Ville G., Herbage D., Eloy R. (1987) Ultrastructural immunolocalization of elastic fibers in rat blood vessels using the protein A-gold technique. J. Histochem. Cytochem. 35, 15-21.
UniProt: P15502 (ELN_HUMAN).
Caution: *These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
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