Application Note: ERK1 N-term blocking peptide is suitable as a control for polyclonal or monoclonal Anti-ERK1 in immunological assays.
Concentration Value: 1.0 mg/mL
Western Blot Dilution: 50ng
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Physical State: Lyophilized
Purity and Specificity: Purity was determined to be greater than 95% specific peptide by analysis by HPLC and by reducing and non-reducing SDS-PAGE.
Background: Mitogen activated protein kinase 3, also known as MAPK3, ERK, or ERK1, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. ERK1 is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.
Low Endotoxin: No
Other: Dot Blot