Exatecan intermediate 11

Product Description: Exatecan intermediate 11 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].

Applications: Cancer-programmed cell death

Formula: C13H13FN2O3

References: [1]Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.

Molecular Weight: 264.25

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin;Topoisomerase

• SKU: MEXHY-49861-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-49861-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK