Clone Name: MFL3
Product Description: The MFL3 monoclonal antibody reacts with mouse CD178, a 40 kD member type-II transmembrane protein and member of the TNF family of proteins. CD178 is also known as Fas ligand, FasL, Apo-1 ligand, and CD95 ligand. CD178 is expressed on activated T cells and and natural killer (NK) cells and also tissue at immune privileged sites such as the eye and testis. FasL interacts with its receptor CD95 (Fas) to initiate apoptotic cell death and is thought to play a role in T cell development, immune response regulation, and cell-mediated cytotoxic responses. This MFL3 clone has been reported to block CD178/CD96 induced apoptosis.
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 0/31
Form: Liquid
Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Uniprot ID: P41047/Q544E9
Purification: Purified by affinity chromatography
Conjugation: PE
Full Name: Fas ligand (TNF superfamily, member 6)
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