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Clone Name: 6F6G11
Application Note: WB: 1:500-1:2000. FACS: 1:200-1:400. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 153
Form: Liquid
Buffer (with preservative): PBS, 0.05% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Uniprot ID: Q8NHM5
Antigen Species: Human
Immunogen: Purified recombinant fragment of human FBXL10 (AA: 457-555) expressed in E. Coli.
Purification: Purified IgG2b
Conjugation: Unconjugated
Full Name: lysine demethylase 2B