FGF-22

Product Description: Fibroblast Growth Factor 22 (FGF-22) is a mediator of synaptogenesis in the adult nervous system and functions to regulate synapse formation and maturation. FGF-22 is expressed in the inner hair cell and functions to maintain ribbon synapse number to protect functional hearing. In the hippocampus, FGF-22 promotes excitatory synapse formation through binding the FGFR2b and FGFR1 β receptors. FGF-22 is also required for axonal circuit remodeling after spinal cord injury.

Growth Factor AA Sequence: MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTV DCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS

• SKU: CGSGFH68-5
• Manufacturer: Cell Guidance Systems
• Manufacturer SKU: GFH68-5
• Package Unit: 5 μg
• Quantity Unit: STK
• Reactivity: Human