Application Note: WB: 0.5-2μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 59
Positive Control: The peptide used to generate this antibody is available for purchase (GTX95551-PEP).
Specificity/Sensitivity: This antibody is expected to recognise all three reported isoforms (NP_001036194.1; NP_001036212.1; NP_005239.1).
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Uniprot ID: P09769
Antigen Species: Human
Immunogen: Peptide with sequence C-TSAEPQYQPGDQT, from the C Terminus of the protein sequence according to NP_001036194.1; NP_001036212.1; NP_005239.1.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: FGR proto-oncogene, Src family tyrosine kinase
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