Fmoc-Lys(Pal-Glu-OtBu)-OH, CAS 1491158-62-3

Product Description: Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys(Pal-Glu-OtBu)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Applications: Cancer-programmed cell death

Formula: C46H69N3O8

References: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985./[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

CAS Number: 1491158-62-3

Molecular Weight: 792.06

Compound Purity: 98.61

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-W045822-1G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W045822-1G
• Package Unit: 1 g
• Quantity Unit: STK