Calculated MW: 60
Form: Liquid
Buffer (with preservative): PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.
Antigen Species: Human
Immunogen: The antiserum was produced against synthesized peptide derived from human Fyn around the phosphorylation site of Tyr530.
Purification: Purified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns
Conjugation: Unconjugated
Full Name: FYN oncogene related to SRC, FGR, YES
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