Clone Name: 9-13
Light Chain: Kappa
Application Note: WB: 1:500. ICC/IF: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 143
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, no preservative.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Uniprot ID: O14976
Antigen Species: Rat
Immunogen: Recombinant rat GAK (kinase domain, 1-430)
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: cyclin G associated kinase
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