Application Note: WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 187
Positive Control: mouse brain , rat brain
Form: Liquid
Buffer (with preservative): PBS, 20% Glycerol, 0.025% ProClin 300.
Concentration: 1.04 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
Uniprot ID: Q9P2K8
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the center region of human GCN2. The exact sequence is proprietary.
Purification: Purified by antigen-affinity chromatography.
Conjugation: Unconjugated
Full Name: eukaryotic translation initiation factor 2 alpha kinase 4
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