Products from BPS Bioscience require a minimum order value above 400€
Assay Conditions: GITR-biotin binding to GITRL was confirmed using the GITRL:GITR[Biotinylated] Inhibitor Screening Assay Kit (BPS Cat. #72061).
Description: Human secreted GITR, also known as Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, and CD357, GenBank Accession No. NM_004195, a.a. 26-161 expressed in a HEK293 cell expression system, fused at the C-terminus to the Fc portion of human IgG1, and enzymatically biotin-labeled using Avi-tag™ technology. MW = 43 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_004195
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Human IgG1)
Uniprot: Q9Y5U5
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1.Shimizu, J., et al., Nat. Immunol. 2002; 3: 135-142.2.Ko, K., et al., J. Exp. Med. 2005; 202(7): 885-891.