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Clone Name: HL2297
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 53
Positive Control: mouse brain
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
Uniprot ID: P43220
Antigen Species: Human
Immunogen: Synthetic peptide of human GLP1R.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: glucagon like peptide 1 receptor
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