Gly-Gly-Gly-PEG4-azide

Product Description: Gly-Gly-Gly-PEG4-azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C16H31N7O7

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

Molecular Weight: 433.46

Compound Purity: 99.79

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker

• SKU: MEXHY-145066-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145066-10
• Package Unit: 10mg
• Quantity Unit: STK