Abbreviation: GNA11
Target Synonym: GNA11;FBH;FBH2;FHH2;GNA-11;HHC2;HYPOC2
Conjugation: Unconjugated
UNIProt ID: P29992
Background: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human GNA11
Dilution: IF 1:50-1:200