Calculated MW: 261
Form: Liquid
Buffer (with preservative): PBS, 2% sucrose, 0.09% sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016]
Uniprot ID: Q9UGM3
Antigen Species: Human
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DMBT1.
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: deleted in malignant brain tumors 1
English
Deutsch
