Clone Name: GT122
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 93
Form: Liquid
Buffer (with preservative): PBS, 20% Glycerol, no Preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
Uniprot ID: Q16665
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the C-term region of human HIF1 alpha. The exact sequence is proprietary.
Purification: Affinity purified by Protein G.
Conjugation: Unconjugated
Full Name: hypoxia inducible factor 1 subunit alpha
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