Abbreviation: HIST1H3D
Target Synonym: H3.4;H3/g;H3FT;H3t;HIST3H3;Histone H3;HIST1H3A
Conjugation: Unconjugated
UNIProt ID: Q16695/P68431
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human HIST1H3D
Dilution: WB 1:500-1:2000
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