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Application Note: WB: 1:1000. ICC/IF: 1:100. IHC-P: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 22
Form: Liquid
Buffer (with preservative): PBS, 50% glycerol, 0.09% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Uniprot ID: Q9UJY1
Antigen Species: Human
Immunogen: Human HSP22
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: heat shock protein family B (small) member 8
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