Clone: 29E.2A3.
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
Recommended Usage: CD274 Capture Beads are intended for the immunoisolation (immunomagnetic or FACS) and FCM analysis of pre-enriched CD274+ human exosomes.
Description: Exosomes are small extracellular vesicles that are released from cells upon fusion of an intermediate endocytic compartment, the multivesicular body, with the plasma membrane. They are thought to provide a means of intercellular communication and of transmission of macromolecules between cells allowing the spread of proteins, lipids, mRNA, miRNA and DNA and as contributing factors in the development of several diseases1. Yáñez-Mó M, Siljander P, Andreu Z, Bedina Zavec A, Borràs F, Buzas E et al. Biological properties of extracellular vesicles and their physiological functions. Journal of Extracellular Vesicles. 2015;4(1):27066.
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