Species: Human
Application Note: Specific activity is > 5,000 pmol/min/μg, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of Z-GP-AMC per minute at pH 7.5, at 37ºC.
Calculated MW: 88
Form: Liquid
Buffer (with preservative): PBS (pH7.4), 20% Glycerol, no preservative.
Concentration: 0.25 mg/ml (Please refer to the vial label for the specific concentration.)
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Background: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Uniprot ID: Q12884
Region Sequence: His-Tagged; 26-760aa (Q12884, NP_004451.2)
ExpressionSystem: Baculovirus
Conjugation: Unconjugated
Full Name: fibroblast activation protein alpha
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