Species: Human
Form: Liquid
Buffer (with preservative): PBS, 20% Glycerol, no preservative.
Concentration: batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
Uniprot ID: P22455
Region Sequence: C-terminal 10 x His tagged ; 22-369 aa (Uniprot #P22455)
ExpressionSystem: HEK293 cells
Conjugation: Unconjugated
Full Name: fibroblast growth factor receptor 4
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