Species: Human
Application Note: Measured by its ability to cleave the fluorogenic peptide substrate, Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2. The specific activity is > 60 pmol/min/μg.
Form: Lyophilized powder
Buffer (with preservative): Batch dependent (please contact us for details)
Concentration:
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme may degrade collagen type IV, fibronectin, fibrinogen, and beta-casein, and activate matrix metalloproteinase-9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The encoded protein may promote cell invasion in multiple human cancers. [provided by RefSeq, May 2016]
Uniprot ID: Q9NRE1
Region Sequence: No tag; Thr90-Pro261 (NP_068573.2)
ExpressionSystem: E. coli
Conjugation: Unconjugated
Full Name: matrix metallopeptidase 26
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