Products from BPS Bioscience require a minimum order value above 400€
Amino Acid Sequence: RGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQGRAICSDPNNKRVKNAVKYLQSLERS
Background: Thymus and activation-regulated chemokine (TARC) is a recently identified CC chemokine that is expressed constitutively in thymus and transiently in stimulated peripheral blood mononuclear cells. TARC functions as a selective chemoattractant for T-cells that express a class of high affinity receptors binding TARC. The chemokine TARC is a ligand for the chemokine receptor CCR4 expressed on T helper (Th)2- type CD4 T cells.
Biological Activity: Determined by its ability to chemoattract human T cells using a concentration range of 2.0-40.0 ng/ml.
Description: Recombinant TARC (CCL17) is a disulfide-linked monomeric protein consisting of 72 amino acid residues and migrates as an approximately 8 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human TARC (CCL17) mature chain was expressed in E. coli.
Endotoxin Level: <0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Format: lyophilized protein
Formulation: Lyophilized from a 0.2 µm filtered 20 mM phosphate buffer, 100 mM NaCl solution, pH 7.5.
Genbank: Q92583
Purity: ≥98% by SDS-PAGE and HPLC
Reconstitution: Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Storage Stability: The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.
Uniprot: Q92583
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Saeki H, Tamaki K. J Dermatol Sci. 2006 Aug,43(2):75-84.
2. Biragyn A, et al. J Immunother. 2013 May,36(4):258-67.
English
Deutsch
