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Clone Name: HL1957
Light Chain: Kappa
Application Note: ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 155
Specificity/Sensitivity: This antibody was raised against human IGF1R Extracellular domain.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Uniprot ID: P08069
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human IGF1R. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: insulin like growth factor 1 receptor
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