Conjugation: HRP: Horseradish Peroxidase
Description of Target: IKZF2 is associates with Ikaros at centromeric heterochromatin.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IKZF2
Key Reference: Antica,M., (2008) Blood 111 (6), 3296-3297
Molecular Weight: 59kDa
Peptide Sequence: Synthetic peptide located within the following region:
EREASPSNSCLDSTDSESSHDDHQSYQGHPALNPKRKQSPAYMKEDVKALProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Zinc finger protein Helios
Protein Size: 526
Purification: Affinity Purified