Clone Name: AS10
Application Note: FACS: Use 10μl of antibody (10^5-10^6 cells) to stain intracellular human IL1 beta expressed in monocytes and macrophages. Optimal dilutions/concentrations should be determined by the end user.
Specificity/Sensitivity: Does not recognise human IL1 alpha or a panel of other human cytokines
Form: Liquid
Buffer (with preservative): PBS, 0.08% Sodium azide.
Concentration: 0.025 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
Immunogen: Unfortunately, this information is considered to be commercially sensitive
Purification: Protein A purified
Conjugation: FITC
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