Clone Name: MT175
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 31
Specificity/Sensitivity: This antibody is able to detect native and recombinant human IL-1β, binds to the pro-form and active form of IL-1β, and has no cross-reactivity with IL-1α.
Form: Liquid
Buffer (with preservative): PBS, 0.02% Sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Uniprot ID: P01584
Antigen Species: Human
Immunogen: Recombinant human IL-1β
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: interleukin 1 beta
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