Clone Name: MT27 + MT361
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 27
Specificity/Sensitivity: This antibody is able to detect native and recombinant human IL-27. Clone [MT27] binds to IL-27, and clone [MT361] binds to p28, which is part of the IL-27 heterodimer.
Form: Liquid
Buffer (with preservative): PBS, 0.02% Sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]
Uniprot ID: Q8NEV9
Antigen Species: Human
Immunogen: Recombinant human IL-27
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: interleukin 27
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