Ilorasertib, CAS 1227939-82-3

Description: Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).

CAS Number: 1227939-82-3

Formula: C25H21FN6O2S

Molecular Weight: 488,54

References: Curtin ML, et al. Thienopyridine ureas as dual inhibitors of the VEGF and Aurora kinase families. Bioorg Med Chem Lett. 2012 May 1;22(9):3208-12.

• SKU: TGMTQ0059-200mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: TQ0059-200mg
• Package Unit: 200 mg
• Quantity Unit: STK