Description: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 134 amino acids (1-114) with a His Tag of 20 amino acids. IRF-1 regulates gene expression critical to immune response, hematopoiesis and proliferation.