(KD Validated) COX IV Polyclonal Antibody, Rabbit

Abbreviation: COX IV

Target Synonym: COX4I1;COX IV-1;COX4;COX4-1;COXIV;COXIV-1;COX IV

Conjugation: Unconjugated

UNIProt ID: P13073

Background: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human COX IV

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-93369-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-93369-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit