Target: Kir2.1
Conjugate: Unconjugated
Product Type: Monoclonal
Clone Number: S112
Immunogen: Fusion protein amino acids 41-64 and 189-428 of mouse Kir2.1
Swiss-Prot: P35561
Purification: Protein G Purified
Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Concentration: 1 mg/ml
Specificity: Detects ~45kDa. No cross-reactivity against Kir2.2 or Kir2.3.
Cellular Localization: Membrane
Scientific Background: The Kir2.1 inward-rectifier potassium ion channel is encoded by the KCNJ2 gene. A defect in this gene is associated with Andersen-Tawil syndrome (1).
References: 1. Donaldson M.R., Yoon G., Fu Y.H., Ptacek L.J. (2004). Ann. Med. 36 Suppl 1: 92–7.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.