Clone Name: Mer3/22B2
Light Chain: Kappa
Application Note: IHC-Fr: 1:50–1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 344
Specificity/Sensitivity: We do not recommend use of this product for Chicken,Dog,Hamster,Mouse,Pig,Rat.
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: P24043
Antigen Species: Human
Immunogen: Purified protein from placenta.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: laminin subunit alpha 2
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