LE01, CAS 2718125-83-6

Product Description: LE01 is a drug-linker conjugate for ADC. LE01 contains a ADC linker and a DNA topoisomerase I inhibitor DXd (HY-13631D). LE01 can be used to synthesize HER2-targeting ADC (HER2-LE01)[1].

Applications: Cancer-programmed cell death

Formula: C55H61FN10O14

References: [1]Yifan Zhang, et al. Evaluation of Double Self-Immolative Linker-Based Antibody-Drug Conjugate FDA022-BB05 with Enhanced Therapeutic Potential. J Med Chem. 2024 Nov 14;67(21):19852-19873.

CAS Number: 2718125-83-6

Molecular Weight: 1105.13

Research Area: Cancer

Target: Drug-Linker Conjugates for ADC;Topoisomerase

• SKU: MEXHY-168285-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168285-0
• Package Unit: Get quote
• Quantity Unit: STK