Formulation: A solid
Formal Name: [(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2,6-dimethoxy-4,1-phenylene) bis-β-D-glucopyranoside
Purity: ≥98%
Formula Markup: C34H46O18
Formula Weight: 742,7
Shelf life (days): 1460
CAS Number: 573-44-4
Notes: Liriodendrin is a lignan glucoside that has been found in B. diffusa and has diverse biological activities.{72382,72383} It prevents LPS-induced increases in nitrite (NO), prostaglandin E2 (PGE2; Item No. 14010), TNF-α, inducible nitric oxide synthase (iNOS), and COX-2 levels in RAW 264.7 macrophages when used at a concentration of 120 µM.{72382} Liriodendrin (1, 10, or 100 µM) decreases calcium channel currents in a whole-cell patch-clamp assay using isolated frog atrial cells.{72383} It inhibits carrageenan-induced paw edema in rats when administered at a dose of 10 mg/kg.{72382} Liriodendrin increases the latency to paw withdrawal in the hot plate test in mice when administered at a dose of 10 mg/kg.
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